HEREDITER SFEROSITOZ PDF

Important User Information: Remote access to EBSCO's databases is permitted to patrons of subscribing institutions accessing from remote locations for personal, non-commercial use. However, remote access to EBSCO's databases from non-subscribing institutions is not allowed if the purpose of the use is for commercial gain through cost reduction or avoidance for a non-subscribing institution. Source: Journal of Academic Research in Medicine. Abstract: Hemolytic anemia due to erythrocyte membrane disorder has an important place among hereditary anemia. Hereditary spherocytosis HS is one of the most common of them. It is an anemia which is apparent with the spherocyte-shaped erythrocytes and is usually dominantly inherited.

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Hereditary spherocytosis HS is a relatively common hemolytic anemia; most affected individuals have mild or only moderate haemolysis. It is a heterogeneous group of disorders with regard to clinical severity, protein defects and mode of inheritance. There is usually a family history, and a typical clinical and laboratory picture so that the diagnosis is often easily made without additional laboratory tests.

Atypical cases may require measurement of erythrocyte membrane proteins to clarify the nature of the membrane disorder and in the absence of a family history. Mild HS can be managed without folate supplementation and does not require splenectomy. Moderately or severely affected individuals are likely to benefit from splenectomy, which should be performed after the age of years. TR Contact Home. Toggle navigation. Volume : 55 Issue : 1 Year : Copyright Transfer Form.

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