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New therapeutic options in meconium aspiration syndrome. Porto Alegre, RS, Brasil. CEP: E-mail: celiny terra. Randomized and quasi-randomized trials, case control studies, meta-analyses and recently published reviews were selected. Other articles were included for their valuable contribution to the subject. MAS management is initiated with airway aspiration in the delivery room, followed by the ventilatory management required to maintain optimal arterial oxygenation, as well as complications treatment.

Considering evidences showing that meconium mechanical airway obstruction and its inhibitory effect on the surfactant system, the use of surfactant replacement and bronchoalveolar lavage with surfactant suspension are under study. Therefore, it is very important to identify new ventilatory strategies and evaluate whether there are advantages in using surfactant and bronchoalveolar lavage with surfactant suspension in MAS.

Key words: Meconium aspiration syndrome, Pulmonary surfactants, Bronchoalveolar lavage. A SAM continua ocorrendo em pacientes adequadamente aspirados na sala de parto. Surfactante e lavado broncoalveolar.

Khammash et al. Findlay et al. Lotze et al. Paranka et al. Balaraman et al. Cochrane et al. Recentemente, Wiswell et al. Em um relato de casos de SAM com hemorragia pulmonar, Kaneko et al. Surfactant lavage for meconium aspiration syndrome: a pilot study. Pediatrics ; Meconium-stained amniotic fluid and the meconium aspiration syndrome - an update. Pediatr Clin North Am ; Ohama Y, Ogawa Y. Treatment of meconium aspiration sindrome with surfactant lavage in an experimental rabbit model. Pediatr Pulmonol ; Acute respiratory disorders.

Neonatology: pathophysiology and management of the newborn. Guinsburg R, Miyoshi MH. A multicenter, randomized, controlled trial comparing surfaxin lucinactant lavage with standard care for treatment of meconium aspiration syndrome. Pediatr Mod ; Surfactant inhibition in experimental meconium aspiration syndrome. Acta Paediatr ; Surfactant replacement therapy for meconium aspiration syndrome. Pediatr ; Mechanical and chemical damage to lung tissue caused by meconium aspiration.

An experimental model for the study of meconium aspiration of the newborn. Radiology ; Kattwinkel J. Surfactant lavage for meconium aspiration: a word of caution. Inhibition of pulmonary surfactant function by meconium. Am J Obstet Gynecol ; Stable microbubble test for evaluation of surfactant inhibition by meconium, human albumin and blood and restoration of surfactant activity by dextran.

Cagliary: Parma University; Meconium aspiration syndrome: physiological and inflammatory changes in a newborn piglet model. Clark DA. Surfactant displacement by meconium free fatty acids: an alternative explanation for atelectasis in meconium aspiration syndrome.

J Pediatr ; Burchfield DJ. Physiology of resuscitation. Fetal and neonatal physiology. Philadelphia: WB Sauders; Combined effects of high-frequency ventilation and surfactant treatment in experimental meconium aspiration syndrome. Acta Anaesthesiol Scand ; Continuous distending pressure. Assisted ventilation of the neonate. Effects of exogenous surfactant on gas exchange and compliance in rabbits after meconium aspiration.

Liquid ventilation. A randomised control study of partial liquid ventilation after airway lavage with exogenous surfactant in a meconium aspiration syndrome animal model. Surfactant treatment of full-term newborn with respiratory failure. Surfactant therapy in full-term neonates with severe respiratory failure.

Improved pulmonary outcome after exogenous surfactant therapy for respiratory failure in term infants requiring extracorporeal membrane oxygenation.

Multicenter study of surfactant beractant use in the treatment of term infants with severe respiratory failure. Combined obstetric and pediatric approach to prevent meconium aspiration syndrome. Am J Obstet Gynecol Surfactant lavage in a piglet model of meconium aspiration syndrome.

Pediatr Res ; Bronchoalveolar lavage with KL4-surfactant in models of meconium aspiration syndrome. Perfluorocarbon broncho-alveolar lavage and liquid ventilation versus saline broncho-alveolar lavage in adult guinea pig experimental model of meconium inhalation.

Intensive Care Med ; Physiologic response and lung distribution of lavage versus bolus Exosurf in piglets with acute lung injury. Lavage administration of dilute surfactants after acute lung injury in neonatal piglets. Effect of surfactant lavage in a rabbit model of meconium aspiration syndrome.

Acta Paediatr Jpn ; Surfactant therapy and high-frequency jet ventilation in the management of a piglet model of the meconium aspiration syndrome. Surfactant lavage and replacement in meconium aspiration syndrome with pulmonary hemorrage. J Perinat Med ; All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License. Services on Demand Journal. Rua dos Coelhos, How to cite this article.


Tincion de meconio al nacimiento y aspiracion de liquido amniotico y meconio en cachorros




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