ERTAPENEM PACKAGE INSERT PDF

Editor-In-Chief: C. Michael Gibson, M. INVANZ may be administered by intravenous infusion for up to 14 days or intramuscular injection for up to 7 days. Intramuscular administration of INVANZ may be used as an alternative to intravenous administration in the treatment of those infections for which intramuscular therapy is appropriate. A supplementary dose of mg is recommended if ertapenem is administered within 6 hours prior to hemodialysis. There are no data in pediatric patients with renal impairment.

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Medically reviewed by Drugs. Last updated on Feb 13, INVANZ may be administered by intravenous infusion for up to 14 days or intramuscular injection for up to 7 days. Intramuscular administration of INVANZ may be used as an alternative to intravenous administration in the treatment of those infections for which intramuscular therapy is appropriate.

A supplementary dose of mg is recommended if ertapenem is administered within 6 hours prior to hemodialysis. There are no data in pediatric patients with renal impairment. When adult patients on hemodialysis are given the recommended daily dose of mg of INVANZ within 6 hours prior to hemodialysis, a supplementary dose of mg is recommended following the hemodialysis session.

There are no data in patients undergoing peritoneal dialysis or hemofiltration. There are no data in pediatric patients on hemodialysis. When only the serum creatinine is available, the following formula 1 may be used to estimate creatinine clearance.

The serum creatinine should represent a steady state of renal function. Prediction of creatinine clearance from serum creatinine. No dose adjustment recommendations can be made in patients with hepatic impairment [see Use in Specific Populations 8. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to use, whenever solution and container permit.

Variations of color within this range do not affect the potency of the product. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Available for Android and iOS devices. Subscribe to Drugs. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.

We comply with the HONcode standard for trustworthy health information - verify here. Skip to Content. Patients on Hemodialysis When adult patients on hemodialysis are given the recommended daily dose of mg of INVANZ within 6 hours prior to hemodialysis, a supplementary dose of mg is recommended following the hemodialysis session.

Patients with Hepatic Impairment No dose adjustment recommendations can be made in patients with hepatic impairment [see Use in Specific Populations 8. Shake well to dissolve and immediately transfer contents of the reconstituted vial to 50 mL of 0.

Complete the infusion within 6 hours of reconstitution. Shake vial thoroughly to form solution. Immediately withdraw the contents of the vial and administer by deep intramuscular injection into a large muscle mass such as the gluteal muscles or lateral part of the thigh. The reconstituted IM solution should be used within 1 hour after preparation.

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Complicated intra-abdominal infections. Complicated urinary tract infections, including pyelonephritis. Acute pelvic infections including postpartum endomyometritis, septic abortion and post surgical gynecologic infections. Daily Dose IV Adults. Prophylaxis of surgical site infection following elective colorectal surgery. Single intravenous dose given 1 hour prior to surgical incision.

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Ertapenem dosage and administration

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Ertapenem for injection and other antibacterial drugs, Ertapenem for injection should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy. Ertapenem for injection is indicated for the treatment of adult patients and pediatric patients 3 months of age and older with the following moderate to severe infections caused by susceptible isolates of the designated microorganisms [see Dosage and Administration 2 ]. Ertapenem for injection is indicated for the treatment of complicated intra-abdominal infections due to Escherichia coli , Clostridium clostridioforme , Eubacterium lentum , Peptostreptococcus species, Bacteroides fragilis , Bacteroides distasonis , Bacteroides ovatus , Bacteroides thetaiotaomicron , or Bacteroides uniformis.

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Ertapenem for Injection

Send the page " " to a friend, relative, colleague or yourself. We do not record any personal information entered above. IV or IM broad-spectrum carbapenem antibiotic stable against beta-lactamases Used to treat UTI, skin, pelvic, intraabdominal infections and community-acquired pneumonia; used for colorectal surgical prophylaxis Once-daily dosing may be advantageous, but no P. Consider transitioning to an appropriate oral therapy after at least 3 days of parenteral therapy, once clinical improvement has been demonstrated. Guidelines recommend ertapenem for 4 to 7 days for mild-to-moderate community-acquired infections, including perforated or abscessed appendicitis. Guidelines recommend ertapenem for 4 to 7 days for community-acquired infections. Guidelines recommend ertapenem for mixed necrotizing infections.

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Invanz Dosage

Medically reviewed by Drugs. Last updated on Feb 13, INVANZ may be administered by intravenous infusion for up to 14 days or intramuscular injection for up to 7 days. Intramuscular administration of INVANZ may be used as an alternative to intravenous administration in the treatment of those infections for which intramuscular therapy is appropriate. A supplementary dose of mg is recommended if ertapenem is administered within 6 hours prior to hemodialysis. There are no data in pediatric patients with renal impairment. When adult patients on hemodialysis are given the recommended daily dose of mg of INVANZ within 6 hours prior to hemodialysis, a supplementary dose of mg is recommended following the hemodialysis session.

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Ertapenem for Injection

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